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Ana Popović (Serbian Cyrillic: Ана Поповић) (born Belgrade, Serbia in 1976) is a Blues-guitarist and singer.

Popović's Her father first introduced her to the blues, through an extensive record collection and sessions hosted at the family home. Popović founded her first serious band at age nineteen. Within a year, she was playing outside of Yugoslavia and opening shows for American blues icons like Junior Wells. By 1998, her band was doing 100 shows annually and appearing regularly on Yugoslavian television. Her debut CD, Hometown, provided a first glimpse of her talents as a singer and guitarist.

In 1999, Popović relocated to the Netherlands to study jazz guitar. She quickly became a fixture on the Dutch blues scene and soon ventured into neighboring Germany. With Comfort to the Soul (2003), Popović delivered another diverse package of blues, rock, soul and jazz.