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Frank Edwards (March 20, 1909 March 22, 2002) was an American blues guitarist, harmonica player and singer. He was variously billed as Mr. Frank, Black Frank and Mr. Cleanhead.

F R A N K   E D W A R D S, source: Sheldon Harris: Blues Who's Who.- New York 1979, p. 171; photo by George MitchellEdwards was born in Washington, Georgia.

He recorded for three record labels in his career; Okeh Records in 1940, Regal Records in 1949, and Trix Records in the mid-1970s. Some more recent sessions were done for the Music Maker Relief Foundation. His most noted recordings were "Three Women Blues" and "Terraplane Blues".

Frank Edwards died of a heart attack in Greenville, South Carolina, while being driven back to his Atlanta, Georgia home, after completing his final recordings at the age of 93.