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Sonny Landreth (born February 1, 1951) is a American blues musician from southwest Louisiana who is especially known as a slide guitar player. He was born in Canton, Mississippi, but soon after, his family moved to Jackson, Mississippi, before settling in Lafayette, Louisiana. When he is not touring and performing, he resides in Breaux Bridge, Louisiana.

Although Landreth is an extremely competent guitarist in the conventional form, he is most well-known for his slide playing. Landreth has developed a technique where he also frets notes and plays chords and chord fragments behind the slide while he plays. Landreth plays with the slide on his little finger, so that his other fingers have more room to fret behind the slide. He's also known for his unique right-hand technique, which involves tapping, slapping, and picking strings, using all of the fingers on his right hand.

Landreth has worked steadily for decades and amassed a following among his fans and peers. Eric Clapton has said he is "probably the most underestimated musician on the planet and also probably one of the most advanced."

Landreth has also recorded with Jimmy Buffett, and accompanied him on his 2006 and 2007 summer tours.